George Smith was born in Wellington, Somerset, and educated at Oxford, In 1841 he was appointed vicar of Goole, Yorkshire. In 1844 Smith and Thomas McClatchie sailed to China as the first two Christian Missionary Society missionaries in that country, arriving in Shanghai in September of that year. Poor health forced an early return to England, but Smith's Narrative of his period in China was published in 1847. In 1849 was made bishop of the new diocese of Victoria, Hong Kong, and warden of the newly founded St Paul's Missionary College. His diocese included the whole of China and Japan. He learned Mandarin, and became fluent enough to conduct services in it. Smith left Hong Kong for the last time in 1864, retiring from the bishopric early the next year. He died in 1871 at his home in Blackheath, Kent.